Patents

Obendorf, R.L. and Horbowicz, M. (1998) Preparation of fagopyritols and uses therefor. International Patent Publication Number WO 98/50049. International Publication Date: 12 November 1998. Pages 1-77.
Abstract: The present invention describes isolated Fagopyritol A1, isolated Fagopyritol A2, and isolated Fagopyritol B3. Compositions which include two or more of Fagopyritol A1, Fagopyritol A2, Fagopyritol B1, Fagopyritol B2, Fagopyritol B3, and D-chiro-inositol, at least one of which is an isolated Fagopyritol A1, isolated Fagopyritol A2, or isolated Fagopyritol B3, are also disclosed. Methods for preparing substantially pure Fagopyritol A1, Fagopyritol A2, or isolated Fagopyritol B3, are also described. The fagopyritols can be used to prepare pharmaceutical compositions, the administration of which can be used to treat diabetes.

Obendorf, R.L. and Horbowicz, M. (2000) Preparation of fagopyritols and uses therefor. United States Patent Number 6,162,795. Issued: December 19, 2000. Pages 1-35.
Abstract: The present invention describes isolated Fagopyritol A1, isolated Fagopyritol A2, and isolated Fagopyritol B3. Compositions which include two or more of Fagopyritol A1, Fagopyritol A2, Fagopyritol B1, Fagopyritol B2, Fagopyritol B3, and D-chiro-inositol, at least one of which is an isolated Fagopyritol A1, isolated Fagopyritol A2, or isolated Fagopyritol B3, are also disclosed. Methods for preparing substantially pure Fagopyritol A1, Fagopyritol A2, or isolated Fagopyritol B3, are also described. The fagopyritols can be used to prepare pharmaceutical compositions, the administration of which can be used to treat diabetes.

Obendorf, R.L. and Horbowicz, M. (2001) Preparation of fagopyritols and uses therefor. International Patent Publication Number WO 01/89532. International Publication Date: 29 November 2001. Pages 1-128.
Abstract: The present invention describes isolated Fagopyritol A1, isolated Fagopyritol A3, and isolated Fagopyritol B3. Compositions which include two or more of Fagopyritol A1, Fagopyritol A2, Fagopyritol A3, Fagopyritol B1, Fagopyritol B2, Fagopyritol B3, and D-chiro-inositol, at least one of which is an isolated Fagopyritol A1, isolated Fagopyritol A3, or isolated Fagopyritol B3, are also disclosed. Methods for preparing substantially pure Fagopyritol A1, Fagopyritol A3, isolated Fagopyritol B3, or mixtures thereof from buckwheat are also described. The fagopyritols can be used to prepare pharmaceutical compositions, the administration of which can be used to treat diabetes.

Obendorf, R.L. and Horbowicz, M. (2002) Preparation of fagopyritols and uses therefor. United States Patent Number 6,492,341. Issued: December 10, 2002. Pages 1-49.
Abstract: The present invention describes isolated Fagopyritol A1, isolated Fagopyritol A3, and isolated Fagopyritol B3. Compositions which include two or more of Fagopyritol A1, Fagopyritol A2, Fagopyritol A3, Fagopyritol B1, Fagopyritol B2, Fagopyritol B3, and D-chiro-inositol, at least one of which is an isolated Fagopyritol A1, isolated Fagopyritol A3, or isolated Fagopyritol B3, are also disclosed. Methods for preparing substantially pure Fagopyritol A1, Fagopyritol A3, isolated Fagopyritol B3, or mixtures thereof from buckwheat are also described. The fagopyritols can be used to prepare pharmaceutical compositions, the administration of which can be used to treat diabetes.

Obendorf, R.L. and Ueda, T. (2004) Fagopyritol synthase genes and uses thereof. United States Patent Application Publication US 2004/0038357 A1. Published: February 26, 2004. Pages 1-89.
Abstract: The present invention relates to an isolated DNA molecule encoding a fagopyritol synthase. A method for producing a fagopyritol, an insulin mediator, an insulin mediator analogue, an insulin mediator homologue, or an insulin mediator inhibitor is also described. The method includes providing a fagopyritol synthase, providing a substrate comprising a galactosyl donor and a galactosyl acceptor, and combining the fagopyritol synthase with the substrate under conditions effective produce a fagopyritol, an insulin mediator, an insulin mediator analogue, an insulin mediator homologue, or an insulin mediator inhibitor.

Obendorf, R.L. and Ueda, T. (2004) Fagopyritol synthase genes and uses thereof. International Patent Publication Number WO 2004/037974 A2. International Publication Date: 6 May 2004. Pages 1-170.
Abstract: The present invention relates to an isolated DNA molecule encoding a fagopyritol synthase. A method for producing a fagopyritol, an insulin mediator, an insulin mediator analogue, an insulin mediator homologue, or an insulin mediator inhibitor is also described. The method includes providing a fagopyritol synthase, providing a substrate comprising a galactosyl donor and a galactosyl acceptor, and combining the fagopyritol synthase with the substrate under conditions effective produce a fagopyritol, an insulin mediator, an insulin mediator analogue, an insulin mediator homologue, or an insulin mediator inhibitor.

Obendorf, R.L. and Horbowicz, M. (2004) Preparation of fagopyritols and uses therefor. United States Patent Number 6,825,173 B2. Issued: November 30, 2004. Pages 1-48.
Abstract: The present invention describes isolated Fagopyritol A1, isolated Fagopyritol A3, and isolated Fagopyritol B3. Compositions which include two or more of Fagopyritol A1, Fagopyritol A2, Fagopyritol A3, Fagopyritol B1, Fagopyritol B2, Fagopyritol B3, and D-chiro-inositol, at least one of which is an isolated Fagopyritol A1, isolated Fagopyritol A3, or isolated Fagopyritol B3, are also disclosed. Methods for preparing substantially pure Fagopyritol A1, Fagopyritol A3, isolated Fagopyritol B3, or mixtures thereof from buckwheat are also described. The fagopyritols can be used to prepare pharmaceutical compositions, the administration of which can be used to treat diabetes.

Obendorf, R.L. and Ueda, T. (2006) Fagopyritol synthase genes and uses thereof. International Patent Publication Number WO 2004037974 A3. International Publication Date: 6 April 2006.
Abstract: The present invention relates to an isolated DNA molecule encoding a fagopyritol synthase. A method for producing a fagopyritol, an insulin mediator, an insulin mediator analogue, an insulin mediator homologue, or an insulin mediator inhibitor is also described. The method includes providing a fagopyritol synthase, providing a substrate comprising a galactosyl donor and a galactosyl acceptor, and combining the fagopyritol synthase with the substrate under conditions effective produce a fagopyritol, an insulin mediator, an insulin mediator analogue, an insulin mediator homologue, or an insulin mediator inhibitor.

Obendorf, R.L. and Horbowicz, M. (2008) Preparation of fagopyritols and uses therefor. Canada Patent Number 2,236,641. Issued: 15 July 2008.
Abstract: The present invention describes isolated Fagopyritol A1, isolated Fagopyritol A3, and isolated Fagopyritol B3. Compositions which include two or more of Fagopyritol A1, Fagopyritol A2, Fagopyritol A3, Fagopyritol B1, Fagopyritol B2, Fagopyritol B3, and D-chiro-inositol, at least one of which is an isolated Fagopyritol A1, isolated Fagopyritol A3, or isolated Fagopyritol B3, are also disclosed. Methods for preparing substantially pure Fagopyritol A1, Fagopyritol A3, isolated Fagopyritol B3, or mixtures thereof from buckwheat are also described. The fagopyritols can be used to prepare pharmaceutical compositions, the administration of which can be used to treat diabetes.

Obendorf, R.L. and Ueda, T. (2010) Fagopyritol synthase genes and uses thereof. United States Patent No. 7,807,406 B2. Published: October 5, 2010. Pages 1-108.
Abstract: The present invention relates to an isolated DNA molecule encoding a fagopyritol synthase. A method for producing a fagopyritol, an insulin mediator, an insulin mediator analogue, an insulin mediator homologue, or an insulin mediator inhibitor is also described. The method includes providing a fagopyritol synthase, providing a substrate comprising a galactosyl donor and a galactosyl acceptor, and combining the fagopyritol synthase with the substrate under conditions effective produce a fagopyritol, an insulin mediator, an insulin mediator analogue, an insulin mediator homologue, or an insulin mediator inhibitor.

Obendorf, R.L. and Horbowicz, M. (2013) Preparation of fagopyritols and uses therefor. Japan Patent Number 5,174,308. Published: 2013 January 11.

Obendorf, R.L. and Ueda, T. (2013) Fagopyritol synthase genes and uses thereof. Japan Patent Application No. 2013-10782. Published: 2013 January 17.

Obendorf, R.L. and Ueda, T. (2013) Fagopyritol synthase genes and uses thereof. United States Patent Application No. 14/104,788. Filed: December 12, 2013.

Obendorf, R.L. and Ueda, T. (2013) Fagopyritol synthase genes and uses thereof. United States Patent 8,618,271 B2. Date of Patent: December 31, 2013.

Obendorf, R.L. and Ueda, T. (2016) Fagopyritol synthase genes and uses thereof. United States Patent US 9,376,668 B2. Date of Patent: June 28, 2016.

Obendorf, R.L. and Ueda, T. (2016) Fagopyrum esculentum fagopyritol synthase genes and uses thereof. Canadian Letters Patent 2,483,668. Date of Patent: June 28, 2016.

Obendorf, R.L. and Ueda, T. (2017) Fagopyritol synthase genes and uses thereof. United States Patent US 9,758,804 B2. Date of Patent: September 12, 2017.

Obendorf, R.L. and Ueda, T. (2017) Fagopyritol synthase genes and uses thereof. United States Patent US 9,765,377 B2. Date of Patent: September 19, 2017.

Obendorf, R.L. and Ueda, T. (2017) Fagopyritol synthase genes and uses thereof. United States Patent US 9,771,608 B2. Date of Patent: September 26, 2017.

Obendorf, R.L. and Ueda, T. (2018) Fagopyritol synthase genes and uses thereof. United States Patent US 9,926,581 B2. Date of Patent: March 27, 2018.