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Research Interests:
My research program focuses on root biology and ion transport processes as they relate to mineral nutrient acquisition and plant responses to the environment. In this general area, there are three major projects currently underway:
  1. Research on fundamental aspects of plant mineral nutrient transport with emphasis on improving the accumulation of nutritionally important mineral nutrients in plants (Fe, Zn, Ca) and minimizing the entry of toxic heavy metals (Cd, Pb) into the food chain.
  2. The phytoremediation of heavy metal and radionuclide contaminated soils, both from a basic and applied perspective. This research ranges from investigations into fundamental mechanisms of heavy metal/micronutrient transport and hyperaccumulation to field trials of the phytoremediation of radionuclide contaminated soils.
  3. We currently have a major program dealing with plant responses to abiotic stress, with a primary focus on mechanisms of aluminum toxicity and tolerance for plants growing on acid soils. This project involves an integration of physiological investigations of Al tolerance mechanisms with the molecular mapping and cloning of Al tolerance genes in Arabidopsis and important crop plants ("functional genomics" of Al tolerance).

Plant Physiology Journal Cover

Some of our work on the molecular genetics and physiology of aluminum tolerance was featured on the cover of the May 1998 issue of Plant Physiology. See Larsen et al (1998) and Degenhardt et al (1998) for the publications relating to this research

My research approach involves the interdisciplinary application of methodologies from molecular biology and genetics (cloning of ion transport genes, Al tolerance genes, genes conferring heavy metal tolerance), membrane biophysics involving microelectrode techniques, biochemistry, plant physiology and soil chemistry in order to elucidate underlying mechanisms. An ultimate goal is to identify genes that control important plant traits related to mineral nutrient acquisition and abiotic stress tolerance, in order to facilitate crop improvement in these areas.